Scientific Studies About Vitamin D

Vitamin D Science: What the Research Explores

Vitamin D science looks at how this fat-soluble nutrient may support the body, from bone health to immune function. The studies listed below explore the relationship between vitamin D status and respiratory illness, and they are shared here for educational purposes so you can read the original sources yourself. Vitamin D science by Herbal Results

Why Vitamin D Status Matters

Vitamin D is produced in the skin after sun exposure and is also found in a small number of foods and supplements. According to the NIH Office of Dietary Supplements vitamin D fact sheet, the nutrient plays a role in calcium absorption, bone health and normal immune function. Many people spend most of their time indoors, live at northern latitudes or have darker skin, and these factors can all influence how much vitamin D the body makes. That is one reason researchers continue to measure blood levels of 25(OH)D in large groups of people.

Reading the Studies Below

The vitamin D science references listed below include observational studies, retrospective reviews and meta-analyses. Each type of study answers a different question. Observational research can show that two things appear together, but it cannot prove that one causes the other. A meta-analysis combines the results of several studies to look for patterns, while a retrospective review looks back at existing patient records. When you open each link, take note of the study design, the number of participants and the limitations the authors describe. Responsible reading of vitamin D science means avoiding firm conclusions from a single paper.

Key Themes in Vitamin D Research

Across the vitamin D science studies, a few themes appear again and again. Researchers have examined whether low vitamin D levels are more common in people with severe respiratory illness, whether adequate levels may support a balanced immune response, and how vitamin D may interact with other nutrients. Vitamin K2, for example, is often discussed alongside vitamin D3 because both are involved in how the body handles calcium. These ideas are still being studied, and the results so far do not replace advice from a qualified healthcare professional.

Everyday Ways to Support Healthy Vitamin D Levels

Sensible sun exposure, a varied diet and, where appropriate, supplementation are the most common approaches. Fatty fish, egg yolks and fortified foods contain some vitamin D, but it can be difficult to reach target levels through food alone. A combined formula such as HR Vitamin D3 + K2 may support those who want both nutrients in one daily serving. For broader daily wellness support, some customers also explore HR Maximum Strength Olive Leaf Extract as part of their routine.

Before You Start a Supplement

Vitamin D needs vary from person to person, and taking too much can be harmful. If you are pregnant, take medication or have a health condition, speak with your doctor before changing your routine. A simple blood test can show your current level and help you and your practitioner decide what makes sense for you.

Keep Learning

We will continue to add research on vitamin D science and related nutrients as it becomes available. Browse the studies on this page, follow the links to the original publications, and discuss what you learn with a healthcare provider you trust. These statements have not been evaluated by the Food and Drug Administration, and the products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Vitamin D and Covid-19:

1.  Vitamin D Deficiency as a Predictor of Poor Prognosis in Patients With Acute Respiratory Failure Due to COVID-19. https://pubmed.ncbi.nlm.nih.gov/32772324/

 

2. Low Plasma 25(OH) Vitamin D Level Is Associated with Increased Risk of COVID-19 Infection: An Israeli Population-Based Study. https://www.medrxiv.org/content/10.1101/2020.07.01.20144329v1

3. Vitamin D Insufficiency is Prevalent in Severe COVID-19   https://www.medrxiv.org/content/10.1101/2020.04.24.20075838v1

4.  Vitamin D Levels Appear To Play Role in COVID-19 Mortality Rates:” Patients with severe deficiency are twice as likely to experience major complications.” https://www.sciencedaily.com/releases/2020/05/200507121353.htm

5. COVID-19 Mortality Risk Correlates Inversely With Vitamin D3 Status, and a Mortality Rate close to Zero could Theoretically Be Achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/34684596/

6. Evidence that Vitamin D Could Reduce Risk of COVID-19 Infections and Deaths. Review on the role of Vitamin D in reducing the risk of respiratory tract infections. https://pubmed.ncbi.nlm.nih.gov/32252338/

7. The Role of Vitamin D in Suppressing Cytokine Storm and Mortality in COVID-19. A retrospective review of the relationship between Vitamin D and Covid-19 infection and mortality. https://www.medrxiv.org/content/10.1101/2020.04.08.20058578v4

 

8.  Vitamin D Insufficiency is Prevalent in Severe COVID-19. Retrospective review. https://www.medrxiv.org/content/10.1101/2020.04.24.20075838v1